Design, Synthesis, and Application of a Water-soluble Photocage for Aqueous Cyclopentadiene-based Diels–Alder Photoclick Chemistry in Hydrogels. Sophia J. Bailey, Erik Hopkins, Kiara D. Rael, Arsalan Hashmi, Juan Manuel Urueña, Maxwell Z. Wilson, and Javier Read de Alaniz. Angewandte Chemie. (Download PDF)

Diels-Alder Photoclick Patterning of Extracellular Matrix for Spatially Controlled Cell Behaviors. Sophia J. Bailey, Erik Hopkins, Naomi J. Baxter, Isobel Whitehead, Javier Read de Alaniz*, and Maxwell Z. Wilson*. Advanced Materials(Download PDF) 

Optogenetic control of the integrated stress response reveals proportional encoding and the stress memory landscape. Taivan Batjargal, Francesca Zappa, Ryan J. Grant, Robert A. Piscopio, Alex, Chialastri, Siddharth S. Dey, Diego Acosta-Alvear, and Maxwell Z. Wilson. Cell Systems. (Download PDF)

Triggered Functional Dynamics of AsLOV2 by Time-Resolved Electron Paramagnetic Resonance at High Magnetic Fields. Shiny Maity, Brad D. Price, Blake C. Wilson, Arnab Mukherjee, Matthieu Starck, David Parker, Maxwell Z. Wilson, Janet E. Lovett, Songi Han, and Mark S. Sherwin. Angewandte Chemie. (Download PDF)


CREST, a Cas13-Based, Rugged,Equitable, Scalable Testing (CREST) for SARS-CoV-2 Detection in Patient Samples. Zach Aralis, Jennifer N. Rauch, Morgane Audouard, Eric Valois, Ryan S. Lach, Sabrina Solley, Naomi J. Baxter, Kenneth S. Kosik, Maxwell Z. Wilson, Diego Acosta-Alvear, and Carolina Arias. Current Protocols(Download PDF) 

Dynamic assembly of the mRNA m6 A methyltransferase complex is regulated by METTL3 phase separation. Dasol Han, Andrew P. Longhini, Xuemei Zhang, Vivian Hoang, Maxwell Z. Wilson, Kenneth S. Kosik. PLOS Biology(Download PDF) 

Extracellular Optogenetics at the Interface of Synthetic Biology and Materials Science. Lisa K. Månsson, Angela A. Pitenis, Maxwell Z. Wilson. Frontiers in Bioengineering and Biotechnology(Download PDF)

Nucleation of the destruction complex on the centrosome accelerates degradation of β-catenin and regulates Wnt signal transmission. Ryan S. Lach, Chongxu Qiu, Erfan Zeyaei Kajbaf, Naomi Baxter, Dasol Han, Alex Wang, Hannah Lock, Orlando Chirikian, Beth Pruitt, Maxwell Z. Wilson. Proclamation of National Academy of Science(Download PDF)

Optogenetic control of the integrated stress response reveals proportional encoding and the stress memory landscape. Taivan Batjargal, Francesca Zappa, Ryan J Grant, Robert A Piscopio, Alex Chialastri, Siddharth S Dey, Diego Acosta-Alvear, Maxwell Z Wilson. Preprint in bioRxiv(Download PDF)

Signaling by the integrated stress response kinase PKR is fine-tuned by dynamic clustering. Francesca Zappa, Nerea L. Muniozguren, Maxwell Z. Wilson, Michael S. Costello, Jose Carlos Ponce-Rojas, Diego Acosta-Alvear. Journal of Cell Biology.(Download PDF) 

Triggered functional dynamics of AsLOV2 by time-resolved electron paramagnetic resonance at high magnetic fields. Shiny Maity, Brad D. Price, C. Blake Wilson, Arnab Mukherjee, Matthieu Starck, David Parker, Maxwell Z. Wilson, Janet E. Lovett, Songi Han, Mark S. Sherwin. Preprint in bioRxiv. (Download PDF) 


Algal p-coumaric acid induces oxidative stress and siderophore biosynthesis in the bacterial symbiont Phaeobacter inhibens. Rurun Wang, Étienne Gallant, Maxwell Z.Wilson, Yihan Wu, Anran Li, Zemer Gitai, Mohammad R. Seyedsayamdost. Cell Chemical Biology. (Download PDF)

Comparison of Severe Acute Respiratory Syndrome Coronavirus 2 Screening Using Reverse Transcriptase–Quantitative Polymerase Chain Reaction or CRISPR-Based Assays in Asymptomatic College Students. Jennifer N. Rauch, PhD; Eric Valois, PhD; Jose Carlos Ponce-Rojas, PhD; Zach Aralis, BS; Ryan S. Lach, BA; Francesca Zappa, PhD; Morgane Audouard, PhD; Sabrina C. Solley, MA; Chinmay Vaidya, BS; Michael Costello, BS; Holly Smith, RN, BSN; Ali Javanbakht, MD; Betsy Malear, MS, RD; Laura Polito, MD; Stewart Comer, MD; Katherine Arn, MD; Kenneth S. Kosik, MD; Diego Acosta-Alvear, PhD; Maxwell Z. Wilson, PhD; Lynn Fitzgibbons, MD; Carolina Arias, PhD. JAMA Network Open(Download PDF) 

Shining Light on Cyclopentadienone−Norbornadiene Diels−Alder Adducts to Enable Photoinduced Click Chemistry with Cyclopentadiene. Sophia J. Bailey, Friedrich Stricker, Erik Hopkins, Maxwell Z. Wilson,and Javier Read de Alaniz. ACS Applied Materials & Interfaces(Download PDF) 

Formation and Function of Liquid-Like Viral Factories in Negative-Sense Single-Stranded RNA Virus Infections. Justin M. Su , Maxwell Z. Wilson, Charles E. Samuel and Dzwokai Ma. Viruses(Download PDF) 

A Scalable, Easy-to-Deploy Protocol for Cas13-Based Detection of SARS-CoV-2 Genetic Material. Jennifer N. Rauch, Eric Valois, Sabrina C. Solley, Friederike Braig, Ryan S. Lach, Morgane Audouard, Jose Carlos Ponce-Rojas, Michael S. Costello, Naomi J. Baxter, Kenneth S. Kosik, Carolina Arias, Diego Acosta-Alvear, Maxwell Z. Wilson. Journal of Clinical Microbiology. (Download PDF) 

A Fast and Accessible Method for the Isolation of RNA, DNA, and Protein To Facilitate the Detection of SARS-CoV-2. Jose Carlos Ponce-Rojas, Michael S. Costello, Duncan A. Proctor, Kenneth S. Kosik, Maxwell Z. Wilson, Carolina Arias, Diego Acosta-Alvear. Journal of Clinical Microbiology(Download PDF) 

Optogenetics in the Hot Seat. Maxwell Z. Wilson. Nature Chemical Biology(Download PDF) 


A Live-Cell Screen for Altered Erk Dynamics Reveals Principles of Proliferative Control. Alexander G. Goglia, Maxwell Z. Wilson, Siddhartha G. Jena, Jillian Silbert, Lena P. Basta, Danelle Devenport, Jared E. Toettcher. Cell Systems. (Download PDF) 

An Optogenetic Platform to Dynamically Control the Stiffness of Collagen Hydrogels. Erik Hopkins, Eric Valois, Alanna Stull, Kristy Le, Angela A. Pitenis, and Maxwell Z. Wilson*. ACS Biomaterials Science & Engineering(Download PDF) 

A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance. James K.Martin, Joseph P.Sheehan, Benjamin P.Bratton, Gabriel M.Moore, André Mateus, Sophia Hsin-JungLi, Hahn Kim, Joshua D.Rabinowitz, Athanasios Typas, Mikhail M.Savitski, Maxwell Z.Wilson, Zemer Gitai. Cell. (Download PDF) 

Engineering combinatorial and dynamic decoders using synthetic immediate-early genes. Pavithran T. Ravindran, Maxwell Z. Wilson, Siddhartha G. Jena & Jared E. Toettcher. Communications Biology. Nature Communications Biology(Download PDF) 

Optogenetic control of protein binding using light-switchable nanobodies. Agnieszka A. Gil, César Carrasco-López, Liyuan Zhu, Evan M. Zhao, Pavithran T. Ravindran, Maxwell Z. Wilson, Alexander G. Goglia, José L. Avalos & Jared E. Toettcher. Nature Communications(Download PDF) 

The proline-rich domain promotes Tau liquid–liquid phase separation in cells.  Xuemei Zhang, Michael Vigers, James McCarty, Jennifer N. Rauch, Glenn H. Fredrickson, Maxwell Z. Wilson, Joan-Emma Shea, Songi Han, and Kenneth S. Kosik. Journal of Cell Biology(Download PDF) 

The impact of SARS-CoV-2 in dementia across Latin America: A call for an urgent regional plan and coordinated response. Agustin Ibanez, Hernando Santamaria-Garcia, Alejandra Guerrero Barragan, Alexander Kornhuber, Alyne Mendonca Marques Ton, Andrea Slachevsky, Antonio Lucio Teixeira, Beatriz Marcela Mar Meza, Cecilia M. Serrano, Carlos Cano, Carolina Arias Gonzalez, Christian Gonzalez-Billault, Christopher Butler,J ulian Bustin, Claudia Duran-Aniotz, Daisy Acosta, Diana L. Matallana, Diego Acosta-Alvear, Dominic Trépel, Elisa De Paula França Resende, Fabricio Ferreira de Oliveira, Francisco Ibanez, Fernanda G. De Felice, Gorka Navarrete, Ioannis Tarnanas, Irene B. Meier, Jerusa Smid, Jorge Llibre-Guerra, Juan J. Llibre-Rodriguez, Laís Fajersztajn, Leonel Tadao Takada, Lissette Duque, Maira Okada de Oliveira, Maria Aparecida Camargos Bicalho, María Isabel Behrens, Maritza Pintado-Caipa, Mario Parra, Maxwell Z. Wilson, Myriam De La Cruz Puebla, Nilton Custodio, Rodrigo Santibanez, Rodrigo Bernardo Serafim, Ronnielly Melo Tavares, Stefanie Danielle Piña Escudero, Tomas Leon Rodriguez, Walter Dawson, Bruce L. Miller, Kenneth S. Kosik. Alzheimer's Association(Download PDF)


Light-based control of metabolic flux through assembly of synthetic organelles.  Evan M. Zhao, Nathan Suek, Maxwell Z. Wilson, Elliot Dine, Nicole L. Pannucci, Zemer Gitai, José L. Avalos  and Jared E. Toettcher . Nature Chemical Biology(Download PDF) 


Lighting up Cancer Dynamics. Pavithran T.Ravindran and Maxwell Z.Wilson. Trends in Cancer.(Download PDF) 


Optogenetic Control of Ras/Erk Signaling Using the Phy–PIF System. Alexander G. Goglia, Maxwell Z. Wilson, Daniel B. DiGiorno, and Jared E. Toettcher. Methods in Molecular Biology. (Download PDF) 

Tracing Information Flow from Erk to Target Gene Induction Reveals Mechanisms of Dynamic and Combinatorial Control. Maxwell Z. Wilson, Pavithran T. Ravindran, Wendell A. Lim, Jared E. Toettcher. Molecular Cell. (Download PDF) 


Enzyme clustering accelerates processing of intermediates through metabolic channeling. Michele Castellana, Maxwell Z Wilson, Yifan Xu, Preeti Joshi, Ileana M Cristea, Joshua D Rabinowitz, Zemer Gitai & Ned S Wingreen. Nature Biotechnology(Download PDF) 


Beyond the cytoskeleton: mesoscale assemblies and their function in spatial organization. Maxwell Z Wilson and Zemer Gitai. Current Opinion in Microbiology(Download PDF)